Xiamen University Study Identifies Menin as Anti-Aging Brain Factor in Mice, Linking Declines to Memory Loss
Updated
Updated · The Indian Express · Jun 6
Xiamen University Study Identifies Menin as Anti-Aging Brain Factor in Mice, Linking Declines to Memory Loss
1 articles · Updated · The Indian Express · Jun 6
Summary
PLOS Biology published a mouse study led by Xiamen University's Lige Leng finding Menin acts as a protective brain factor against ageing-related decline.
Lower Menin levels in the hypothalamus triggered brain inflammation, memory problems, bone loss and other ageing-like changes, pointing to a possible mechanism behind broader physical decline.
Menin, produced from the MEN1 gene, helps regulate cell growth, repair, inflammation and cellular stress, and researchers say its levels may fall with age.
Human relevance remains unproven: clinicians cited in the report said more studies are needed before Menin can be directly targeted for brain-health or anti-ageing treatments.