High Lipoprotein(a) Predicts 7-Year Death and Stroke Risk at 175 nmol/L

6 articles · Updated · Medical Dialogues · May 14

Lp(a) levels of 175 nmol/L or higher emerged as a strong independent predictor of major adverse cardiovascular events over 7 years, including all-cause death, cardiovascular death and stroke.
Adjusted analyses showed the added risk persisted even after accounting for traditional cardiovascular risk factors, with the effect size described as comparable to active smoking.
Myocardial infarction was the main exception: the study found no significant association between elevated Lp(a) and heart attack risk.
The findings, presented in SCAI 2026 research, add to evidence that Lp(a) may help identify cardiovascular risk not captured by standard factors alone.

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