49ers Open 2026 Season Sept. 10 vs Rams in Australia, Add Mexico City Game
Updated
Updated · Niners Nation · May 12
49ers Open 2026 Season Sept. 10 vs Rams in Australia, Add Mexico City Game
13 articles · Updated · Niners Nation · May 12
Sept. 10 is the first confirmed date on San Francisco’s 2026 schedule, with the 49ers set to face the Rams in Australia in the season opener; Los Angeles will be the designated home team.
Mexico City is also confirmed as a second international stop, giving the 49ers two overseas games before the NFL unveils the full regular-season slate on Thursday.
Nine home and eight away opponents are already known through the league’s rotation, including the Chiefs, Eagles, Cowboys and AFC West teams, even though exact weeks remain mostly unannounced.
FanDuel lists San Francisco at 10.5 projected wins and +260 to win the NFC West, suggesting a favorable schedule on paper despite a division race that also features the Seahawks and Rams.
Who is the 49ers' mystery opponent in Mexico City for their crucial December home game?
Will the 49ers' brutal travel schedule sabotage their supposedly easy path through the 2026 season?
Is the 49ers' unprecedented travel a glimpse into the demanding future of the NFL's global era?