FactSet consensus sees 3.53 billion yuan profit on 310.14 billion yuan revenue when the Beijing-based group reports on Tuesday.
That would mark a return to profit from a 2.71 billion yuan fourth-quarter loss, though below the 10.89 billion yuan earned a year earlier.
Analysts expect resilient retail profitability, narrowing food-delivery losses and about 3% revenue growth, while JD.com's Hong Kong-listed shares rose 1.4% in the first quarter.
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