Scientists find testosterone gel with exercise reduces visceral fat after hip fractures
Updated
Updated · ScienceDaily · May 7
Scientists find testosterone gel with exercise reduces visceral fat after hip fractures
10 articles · Updated · ScienceDaily · May 7
The six-month STEP-HI trial, led by Jacob Earp at the University of Connecticut, tracked 66 women aged over 65 recovering from recent hip fractures.
DXA scans showed overall body fat stayed similar in both groups, but women given the topical hormone had lower abdominal visceral fat while controls saw the usual increase.
The findings, published in Obesity Pillars, suggest a targeted way to improve recovery and long-term health, as hip fractures disproportionately affect older women and often lead to lost independence.
As new weight-loss drugs cause muscle loss, could this hormone therapy be a safer alternative for preserving strength in seniors?
A new study shows testosterone targets only dangerous visceral fat. What is the secret behind this highly selective effect?
Gels for men carry warnings for women. How can this therapy be made safe and accessible for older women needing it most?
Selective Visceral Fat Loss Without Muscle Loss: Testosterone Therapy in Elderly Women Recovering from Hip Fracture
Overview
The 2026 STEP-HI trial studied women aged 65 and older recovering from hip fractures who participated in a 6-month supervised exercise program combined with either topical testosterone gel or placebo. The testosterone group showed a significant 10.57% reduction in harmful visceral fat, while the placebo group’s visceral fat increased. This fat loss occurred without changes in total body fat and was linked to testosterone’s effects on fat metabolism and inflammation. Although testosterone did not improve long-distance walking, it showed potential short-term functional benefits but had a higher rate of serious adverse events. Supervised exercise remains essential, and testosterone therapy requires cautious use and further research to confirm safety and long-term benefits.