Researchers find caffeine activates AMPK and extends yeast lifespan
Updated
Updated · SciTechDaily · May 5
Researchers find caffeine activates AMPK and extends yeast lifespan
3 articles · Updated · SciTechDaily · May 5
Queen Mary University of London scientists reported in Microbial Cell that, in fission yeast, caffeine acts through AMPK pathway components Ssp1, Ssp2 and Amk2.
The study found caffeine speeds mitosis and changes stress responses, while Ssp2 phosphorylation and the Ssp1-Amk2 network help cells endure prolonged genotoxic stress.
Researchers said the findings matter because AMPK is conserved in humans and is also targeted by metformin, linking a common dietary compound to ageing and healthspan research.
If caffeine mimics anti-aging drugs, why might it also raise your risk for heart disease and DNA damage?
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