UCL and UCLH researchers report bowel cancer patients stay cancer-free after immunotherapy
Updated
Updated · SciTechDaily · Apr 30
UCL and UCLH researchers report bowel cancer patients stay cancer-free after immunotherapy
8 articles · Updated · SciTechDaily · Apr 30
In the 32-patient UK NEOPRISM-CRC trial, none relapsed after 33 months; 59% had no detectable cancer after pembrolizumab and surgery.
The stage two or three MMR-deficient/MSI-high bowel cancer study tested nine weeks of pre-surgery pembrolizumab instead of post-surgery chemotherapy, with personalised blood tests and immune profiling helping predict response.
Researchers said the approach could improve outcomes for the 10-15% of such bowel cancers with this genetic profile, compared with roughly 25% expected to relapse within three years under standard care.
With a 0% recurrence rate, is the era of chemotherapy for this type of bowel cancer now officially over?
After immunotherapy 'melts away' tumors, could some bowel cancer patients now safely skip debilitating surgery altogether?
If pre-surgery immunotherapy conquers bowel cancer, which other deadly cancers could be the next to fall?
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Overview
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