APOE4 carriers face higher Alzheimer's risk but can reduce it
Updated
Updated · South China Morning Post · May 3
APOE4 carriers face higher Alzheimer's risk but can reduce it
9 articles · Updated · South China Morning Post · May 3
About 25% of people carry APOE4, highlighted by actor Chris Hemsworth, and experts say risk can be lowered through lifestyle changes.
The report distinguishes APOE4 from rare familial Alzheimer's disease, which is driven by APP, PSEN1 and PSEN2 mutations and usually causes earlier-onset symptoms.
Familial Alzheimer's accounts for less than 1% of cases, while researchers say more than 100 other genes may influence susceptibility, though many have only small effects.
With new at-home drugs and protective gene discoveries, is Alzheimer's becoming a preventable disease for high-risk individuals?
If lifestyle can reverse early brain changes, should all young adults now be screened for the Alzheimer's gene?
New blood tests predict Alzheimer's years in advance, but who will get access to the breakthroughs that follow?