Dyett, who joined in 2023, said he will become an Operator in Residence at Thrive after leading OpenAI's enterprise and API sales during its rapid expansion.
His exit adds to recent leadership turnover at OpenAI, where Fidji Simo took medical leave, Kate Rouch stepped down, and Brad Lightcap shifted to special projects.
Bill Peebles and Kevin Weil also recently left their roles. Thrive is a longtime OpenAI backer, and OpenAI is valued by private investors at more than $850 billion.
Is the leadership exodus at OpenAI a sign of internal crisis or a calculated realignment for enterprise dominance?
With rivals gaining and projects cut, has OpenAI's original mission been sacrificed in its pursuit of profit and a potential IPO?
Can OpenAI's new enterprise-first strategy overcome its legal battles and the growing threat from open-source AI competitors?