The British actor appears in a teaser for Saturday's episode, joking about last year's US SNL sketch that mocked her teeth and drew an apology.
Wood had called the 2025 sketch "mean and unfunny" after Sarah Sherman wore exaggerated fake teeth and a Manchester accent in a White Lotus parody.
The hosting role is framed as Wood reclaiming the narrative after years of comments about her appearance, as she heads into the TV Baftas with two nominations.
How did Aimee Lou Wood turn a 'mean' US sketch into a triumphant UK hosting gig?
With its producer calling it superior, is the UK's SNL poised to eclipse its American parent?