GLP-1 medications drive mainly fat loss with modest muscle loss

13 articles · Updated · Medical News Today · May 1

Researchers reviewed 36 studies and found adults lost about 9% of starting weight after three months, with reduced abdominal fat, waist circumference and BMI.
After 12 months, visceral fat and total fat mass fell substantially, while lean body mass declined relatively modestly compared with overall body-weight loss.
The findings may ease concerns as GLP-1 use grows after FDA approval of a Wegovy pill, though experts still urge protein intake, resistance training and further study of long-term muscle effects.

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