University of Utah researchers find PapB enzyme that strengthens peptide drugs
Updated
Updated · Vocal · Apr 28
University of Utah researchers find PapB enzyme that strengthens peptide drugs
10 articles · Updated · Vocal · Apr 28
The team said PapB links therapeutic peptides into tight ring structures through macrocyclization, a change that could help drugs such as Ozempic stay active longer.
Longer-lasting peptide medicines could improve effectiveness and reduce how often patients need prescriptions, potentially lowering treatment costs for expensive weight-loss drugs.
The report frames the finding as early promise for peptide-based therapies, though it provides no clinical trial results or timeline for use in approved medicines.
Could this discovery unlock a new generation of affordable drugs for Alzheimer's and other chronic diseases?
Can a new enzyme make weight loss drugs affordable, or will it just create a more expensive, longer-lasting pill?