The list ranges from romances and hallucinations to AI-caused deaths, lawsuits, vampirism and fears Dr Michael "Robby" Robinavitch could be sectioned, killed or already dead.
Other speculation centres on Dr Trinity Santos, Dr Baran Al-Hashimi, Dr Jack Abbot, returning resident Frank Langdon and an abandoned baby at Pittsburgh Trauma Medical Center.
The article frames the theories as a sign of the HBO Max medical drama's breakout popularity, with its real-time emergency-room format helping make it one of television's most discussed shows.
Is a doctor's on-screen breakdown just a plot, or a warning about a real-world crisis?
Does TV's 'gritty realism' glamorize the very physician burnout it claims to critique?
When medical AI is 98% accurate, who is to blame for the fatal 2%?