Mayo Clinic researchers identify two early life stages for dementia symptom onset
Updated
Updated · HuffPost UK · Apr 29
Mayo Clinic researchers identify two early life stages for dementia symptom onset
5 articles · Updated · HuffPost UK · Apr 29
The study, involving 2,082 participants in the Mayo Clinic Study of Ageing, found cognitive decline begins around age 50, with amyloid and tau changes emerging in the 60s and early 70s.
Researchers observed two critical windows: early 60s for cognition and amyloid PET changes, and late 60s to early 70s for blood and neurodegeneration markers, suggesting new opportunities for earlier detection.
The findings may help refine dementia diagnosis and screening, as most cases are currently detected years after symptoms begin, and could inform future prevention and treatment strategies using blood biomarkers.
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