Updated
Updated · MarketWatch · Apr 29
Alector discontinues Phase 2 trial of nivisnebart for early Alzheimer's disease
Updated
Updated · MarketWatch · Apr 29

Alector discontinues Phase 2 trial of nivisnebart for early Alzheimer's disease

9 articles · Updated · MarketWatch · Apr 29
  • The Phase 2 PROGRESS-AD trial, co-developed with GSK, is being halted as it is unlikely to achieve its primary endpoint of slowing disease progression.
  • Alector's decision reflects challenges in developing effective treatments for Alzheimer's, disappointing patients and families affected by the disease.
  • Despite this setback, Alector states it remains committed to advancing other neurodegenerative disease programs.
How will this latest failure affect Alector’s crucial partnership with pharma giant GSK?
Alector's drug targeted a high-risk gene. Was this a bold scientific failure or a reckless business gamble?
With another Alzheimer's drug failing, is the entire research strategy for the disease fundamentally flawed?
Alector's stock is high despite huge losses. Is this a bubble or faith in its next big drug?
After so many high-profile setbacks, will investment in Alzheimer's research begin to dry up?
Could AI and gene editing succeed where traditional Alzheimer's drug trials have repeatedly failed?