The FTSE 100 closed at 10,213.11 on Wednesday, with St. James's Place PLC dropping 5.99% and DCC PLC rising 9.29%.
Other notable declines included GSK PLC, Persimmon PLC, Fresnillo PLC, and Howden Joinery Group PLC, while Intertek Group PLC and WPP PLC posted gains.
The British pound weakened against both the dollar and euro, Brent crude oil rose 6.1%, and the 10-year gilt yield increased to 5.101%.
St. James's Place stock fell despite good results. Is its high-fee model under threat?
With public markets falling, are private investments now the safer bet for wealth growth?
Can the Bank of England control inflation driven by a massive global energy shock?
The world just lost 10 million oil barrels daily. Can reserves prevent a global recession?
Is the market overreacting to the Iran crisis, creating major buying opportunities?
Will soaring oil prices finally force Europe's rapid switch to renewable energy?