Updated
Updated · 3D Printing Industry · Jul 22
PRISM-LT Develops 3D Bioprinting for 3 Living Tissues, Targeting Bone Marrow Models and Cultivated Meat
Updated
Updated · 3D Printing Industry · Jul 22

PRISM-LT Develops 3D Bioprinting for 3 Living Tissues, Targeting Bone Marrow Models and Cultivated Meat

2 articles · Updated · 3D Printing Industry · Jul 22

Summary

  • PRISM-LT says it can bioprint living bone, fat and muscle tissue using tiny capsules that combine cells, gel scaffold and engineered microbes, with each print taking minutes to an hour before about three weeks of maturation.
  • Inside those capsules, the microbes detect stem-cell changes and release growth factors that steer development, an attempt to solve bioprinting’s core problem of shaping living tissue without killing cells or losing control of what they become.
  • The EU-funded project can currently make about 1 square centimetre of thin tissue and is working toward a 1-cubic-centimetre block, while researchers say keeping microbes and stem cells alive together remains the hardest technical hurdle.
  • Its first targets are bone-and-fat tissue for 3D bone marrow models in leukaemia drug research and muscle-fat structures for marbled cultivated meat, where texture has been a major barrier to consumer acceptance.
  • Running through 2027, the project is already engaging the European Innovation Council and the European Medicines Agency because materials combining living cells and genetically modified microbes do not fit neatly under existing food or medicine rules.

Insights

Can microbe-guided bioprinting really scale from a 1 cm lab tissue to usable bone marrow models and marbled cultivated meat?
Will regulators treat these printed tissues as medicine, food, or something entirely new as PRISM-LT pushes living materials toward market use?
What happens when stem cells and engineered yeast share one printed capsule—and could that unlock better leukaemia drugs and tastier cultivated meat?