Daily Inulin Cut Knee OA Pain in 117-Adult Trial as Dropouts Fell to 3.6%

1 articles · Updated · ScienceDaily · Jul 25

A six-week randomized trial in 117 adults found daily inulin eased knee osteoarthritis pain and improved grip strength, while digital physiotherapy also reduced pain but did not boost those other measures.
Higher butyrate and GLP-1 levels in the inulin group point to a gut-microbiome pathway that may influence inflammation, pain processing and muscle function.
Only 3.6% of supplement users dropped out, versus 21% in the physiotherapy group, suggesting a daily fiber routine may be easier to sustain than exercise-based treatment.
Published in Nutrients, the University of Nottingham study adds early evidence for a gut-muscle-pain link in a condition affecting hundreds of millions worldwide.