Mt Sinai Study Links 46 PFAS Compounds to Higher Child Gut Inflammation
Updated
Updated · The Guardian · Jul 24
Mt Sinai Study Links 46 PFAS Compounds to Higher Child Gut Inflammation
2 articles · Updated · The Guardian · Jul 24
Summary
107 mother-child pairs tracked from pregnancy to as late as age 11 showed higher PFAS exposure around birth correlated with elevated fecal calprotectin, a marker of intestinal inflammation.
46 prevalent compounds from as many as 955 PFAS metabolites were analyzed as mixtures rather than one by one, capturing real-world exposure that included legacy chemicals such as PFOA and PFOS.
The peer-reviewed study is described as the first to examine how prenatal and early-life PFAS exposure affects children during development, extending adult evidence linking the chemicals to bowel disease and inflammation.
PFAS are a class of at least 16,000 persistent 'forever chemicals' tied to cancer, immune disorders and birth defects, and the authors said the findings should inform policies protecting mothers and children despite the study's relatively small sample.