North Carolina Woman Hospitalized 3 Days After 5-Fold GLP-1 Dose From Amble
Updated
Updated · TODAY · Jul 16
North Carolina Woman Hospitalized 3 Days After 5-Fold GLP-1 Dose From Amble
2 articles · Updated · TODAY · Jul 16
Summary
Leslie Gammon, 54, said a compounded GLP-1 dose from telehealth company Amble sent her to the hospital for 3 days and left her with a $9,000 bill.
After emailing that her initial low dose was not curbing hunger, Gammon said she was told to inject 46 units instead of 8; she took 30 units and began vomiting within 2 hours.
Doctors told her she had a GLP-1 overdose, and she said it took a month before she could keep solid food down again.
National Poison Data System figures show nearly 23,000 calls tied to injectable GLP-1 overdoses or side effects from 2019 to 2025, up almost 1,500%, though the data does not separate telehealth from in-person prescribing.
Doctors and compounders say the case highlights weak oversight around cheaper compounded GLP-1s sold online, which are not FDA-reviewed for safety and can involve confusing syringe measurements.
With poison calls up 1,500%, can the 'Wild West' of online weight-loss prescriptions be tamed before more patients are harmed?
Are cheaper, unregulated weight-loss drugs a dangerous gamble or a necessary risk for patients priced out of the market?
GLP-1 Medication Errors Explode: Telehealth, Compounded Drugs, and Systemic Failures
Overview
This report highlights the growing risks of compounded GLP-1 drugs obtained through telehealth, illustrated by the case of Leslie Gammon, who suffered an overdose after using two online services and subsequently stopped the medication. As GLP-1 prescriptions for weight loss have quadrupled in recent years, the U.S. has seen a dramatic spike in overdoses and poison control calls. The rapid rise in telehealth prescribing, combined with less regulated compounded drugs and self-administered dosing, has led to more errors and adverse events. These trends underscore the urgent need for better oversight, patient education, and safer prescribing practices.