Cedars-Sinai Study Links 5 Cups of Coffee to 47% Lower Liver Cancer Risk
Updated
Updated · SciTechDaily · Jul 12
Cedars-Sinai Study Links 5 Cups of Coffee to 47% Lower Liver Cancer Risk
2 articles · Updated · SciTechDaily · Jul 12
Summary
354,957 UK Biobank adults followed for a median 13 years showed lower rates of cirrhosis, liver cancer and liver-related death among heavier coffee drinkers.
Five or more cups a day was associated with 32% lower cirrhosis risk, 47% lower liver cancer risk and 42% lower liver-related death versus no coffee.
MRI scans and blood-protein analyses pointed to possible mechanisms: coffee drinkers had less liver fat, iron, fibrosis and inflammation, with protein patterns tied to healthier liver function.
Benefits appeared even at 1 to 2 cups and were strongest around 3 to 4 cups; similar results for caffeinated and decaf suggest compounds beyond caffeine may matter.
Cedars-Sinai said the observational study cannot prove cause and does not justify starting coffee solely for liver protection, with prevention still centered on weight, alcohol, exercise and metabolic health.