Japanese Team Finds Frog Bacterium Wipes Out 100% of Mouse Tumors in 1 Dose
Updated
Updated · Good News Network · Jul 12
Japanese Team Finds Frog Bacterium Wipes Out 100% of Mouse Tumors in 1 Dose
2 articles · Updated · Good News Network · Jul 12
Summary
Ewingella americana, isolated from a Japanese tree frog, completely eliminated colorectal tumors in mice after a single intravenous dose, the team led by Professor Eijiro Miyako reported in Gut Microbes.
45 bacterial strains taken from frogs, newts and lizards were screened, and 9 showed anti-tumor activity; E. americana stood out by directly killing cancer cells and triggering immune-driven tumor destruction.
The bacterium outperformed anti-PD-L1 therapy and liposomal doxorubicin in the mouse study, while showing a 1.2-hour blood half-life, no organ colonization and no chronic toxicity over 60 days.
Researchers now plan to test the approach in breast cancer, pancreatic cancer and melanoma, while refining delivery through dose fractionation, intratumoral injection and combinations with existing therapies.
A single dose of frog bacteria cured cancer in mice. When can we expect this groundbreaking therapy to begin human trials?
A tree frog bacterium erases tumors in mice. What's the hidden danger preventing it from becoming a human cure?
This 'living medicine' from a frog outperforms standard cancer drugs. Will nature-based therapies now eclipse lab-created ones?
Naturally Occurring Bacterium *Ewingella americana* Completely Eradicates Colorectal Tumors in Mice: A Paradigm Shift in Cancer Therapy
Overview
On July 12, 2026, researchers from the Japan Advanced Institute of Science and Technology revealed that Ewingella americana, a bacterium isolated from the gut of a Japanese tree frog, can completely eliminate colorectal tumors in mice. Their innovative approach involved isolating and cultivating the bacterium, then delivering it intravenously to directly attack tumors. This breakthrough marks a major shift in cancer research, as Ewingella americana shows extraordinary anti-cancer potential and stands out as a promising candidate for future cancer treatments, offering new hope beyond traditional therapies.