Lancet Study of 123,940 Finds Statins Do Not Raise Most Side-Effect Risks
Updated
Updated · The Independent · Jul 3
Lancet Study of 123,940 Finds Statins Do Not Raise Most Side-Effect Risks
3 articles · Updated · The Independent · Jul 3
Summary
Data from 123,940 people in 19 placebo-controlled trials found no significant increased risk from statins for nearly all side effects listed in package leaflets.
The Lancet study tracked patients for an average 4.5 years after treatment began and specifically found no meaningful rise in depression, sleep problems, fatigue or headaches.
Statins lower LDL cholesterol and triglycerides, helping prevent plaque buildup and cut the risk of heart attacks and strokes.
UK clinicians typically recommend statins when a 10-year cardiovascular risk reaches 10% or more, though liver disease, pregnancy, some muscle disorders and drug interactions can limit use.
Patients are usually monitored with blood tests before treatment and again within six to 12 months, and clinicians say the drugs work best alongside diet, exercise and smoking cessation.