Study Links 1-Year Melatonin Use to 89% Higher Heart Failure Risk

1 articles · Updated · news.laodong.vn · Jun 25

More than 130,000 adults were analyzed, and those using melatonin continuously for over a year showed an 89% higher five-year heart failure risk than non-users.
Hospitalization risk was also markedly higher: long-term users were nearly 3.5 times more likely to be hospitalized for heart failure.
Researchers said the findings show an association, not proof that melatonin causes cardiovascular harm, and noted a key limitation: many U.S. users buy it without prescriptions, which may blur the control group.
Most current guidance treats melatonin as safe mainly for short-term use of one to two months, while experts called for clinical trials and urged people—especially those with cardiovascular risks—not to use it long term without medical advice.