Michigan Study Finds 88% of 200 Men on Testosterone Missed Treatment Criteria

3 articles · Updated · Business Insider · Jun 13

Only 12% of 200 men prescribed testosterone at a University of Michigan clinic met guideline-based criteria, leaving 176 potentially overprescribed under the study.
Two blood tests confirming testosterone below 300 nanograms per deciliter are typically required, yet some treated patients also had conditions such as sleep apnea or prostate cancer that can complicate therapy.
Testosterone replacement can suppress the body's own hormone production and raise risks including infertility, elevated red blood cells, heart attack, stroke, and potentially faster prostate tumor growth.
TRT use has quadrupled over three decades to as many as 11 million Americans, as social-media "T-maxxing" and wellness marketing fuel demand.
Doctors say the picture is still nuanced: some men are undertreated, not just overtreated, and the American Urological Association is preparing a major guideline update within the next year or two.

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Business Insider1d ago

University of Michigan Study Finds 88% of Men Overprescribed Testosterone

health.yahoo.com1d ago

Testosterone is being overprescribed to men — here's who should take it, and when it backfires

X1d ago

Testosterone therapy in men may be overprescribed, inconsistent with clinical guidelines Only a small number of men who were prescribed testosterone therapy received appropriate, guideline-concordant diagnostic testing, according to a study being

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Widespread Inappropriate Testosterone Prescribing: Michigan Study Reveals 88% Non-Adherence to Guidelines

Overview

The University of Michigan study presented at ENDO 2026 highlights significant concerns about widespread inappropriate testosterone prescribing, revealing a systemic issue in current prescribing patterns. Researchers emphasize the critical need for improved guideline-concordant practices to safeguard patient health and prevent avoidable risks. The study aims to thoroughly examine the scale and nature of inappropriate prescribing, focusing on cases where individuals may not have a genuine clinical need for testosterone therapy. It is expected to provide a comprehensive breakdown of prescribing habits by specialty and formulation, as well as rates of inadequate pre-therapy screening and the prevalence of concerning pre-existing conditions, all to inform better clinical practices.

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