Meta-Analysis of 113 Trials Backs Collagen for Skin and Osteoarthritis, Not Blood Sugar
Updated
Updated · TIME · Jun 8
Meta-Analysis of 113 Trials Backs Collagen for Skin and Osteoarthritis, Not Blood Sugar
3 articles · Updated · TIME · Jun 8
Summary
A 2026 meta-analysis of 113 randomized trials involving nearly 8,000 participants found collagen supplements improved skin elasticity and hydration, musculoskeletal health, and osteoarthritis outcomes.
The review found weaker evidence for oral health and cardiometabolic measures, including blood sugar, blood pressure, and cholesterol, suggesting benefits depend heavily on the condition being treated.
Experts said collagen peptides may help by supplying building blocks for the body’s own collagen production, though they stressed supplements are not a cure and work best alongside healthy habits.
Dose and type varied by goal: experts cited 2.5 to 10 g daily of types I and III for skin, and about 40 mg of undenatured type II collagen for joint pain.
The findings add broad support to earlier mixed research, while underscoring that visible or functional changes can take months and should be discussed with a doctor.