Bexorg Tests Drugs on Human Brains for 24 Hours, Targeting 1,600 Samples a Year
Updated
Updated · Futurism · May 31
Bexorg Tests Drugs on Human Brains for 24 Hours, Targeting 1,600 Samples a Year
1 articles · Updated · Futurism · May 31
Hours after death, Bexorg removes human brains and keeps them functioning on its BrainEX system for up to 24 hours to test experimental drugs for Alzheimer’s and Parkinson’s.
The startup says the organs show no coordinated neural activity needed for consciousness; it also administers propofol while preserving key functions with artificial blood, oxygenation and other support.
Bexorg argues the brains offer a more realistic model than mice because they retain 60 to 80 years of human exposures, treatments and disease history before being sliced into hundreds of samples for analysis.
Biohaven has already used 130 Bexorg brains in drug studies, including a Parkinson’s candidate, and plans a clinical trial for another treatment informed by those experiments.
The work extends Bexorg’s earlier 36-hour pig-brain revival research and points to a scaled platform, with the company aiming to process as many as 1,600 human brains annually.
With plans for an AI to test drugs on brain data, are we nearing an end to animal and human trials?
As science keeps human brains 'alive' after death, where do we draw the line between medical progress and ethical nightmare?
From 99% Failure to Breakthroughs: Bexorg’s BrainEx Human Brain Technology Revolutionizes CNS Drug Development
Overview
Traditional brain drug trials have a very high failure rate, mainly because researchers have relied on rodent models instead of real human tissue. This inefficiency leads to billions of dollars in wasted development costs and delays effective treatments for diseases like Alzheimer's and Parkinson's. Bexorg's BrainEx technology is a major breakthrough, providing a new way to test drugs on actual human brain tissue. By offering a more accurate and earlier testing ground, BrainEx promises to speed up drug development, reduce costs, and help bring better treatments to patients faster.