Huang Launches Pilot Study on Circadian Eating and Alcohol as Gut Changes Drive Chronic Inflammation
Updated
Updated · Newswise · May 27
Huang Launches Pilot Study on Circadian Eating and Alcohol as Gut Changes Drive Chronic Inflammation
1 articles · Updated · Newswise · May 27
Summary
Texas Medical Center funding is backing a pilot study led by Xiangsheng Huang on how mistimed eating and alcohol exposure disrupt the gut microbiome and fuel chronic inflammation tied to aging-related disease.
Huang’s team says eating out of sync with circadian rhythms can disturb beneficial gut bacteria, and alcohol may worsen that effect by cutting short-chain fatty acids that help protect the intestinal barrier.
The project centers on “inflammaging” — persistent low-grade inflammation linked to metabolic syndrome, cardiovascular disease and dementia — and will test how those lifestyle factors accelerate the process.
The goal is to identify therapeutic targets and other interventions that could slow chronic inflammation and improve metabolic outcomes, fitting the Digestive Diseases Center’s focus on digestive-system injury, infection and metabolism.